A fun and easy pool to try at your office this season (made famous by Bill Simmons):

10 people play, no more no less.  Each person/team “drafts” three NFL teams, based on who they think will win the most regular season games.

Determine draft order, then use this balanced system to pick the teams:

Team 1 gets 1st pick, 20th pick, and 26th pick
Team 2 gets 2nd, 16th, and 29th
Team 3 gets 3rd, 13th, and 30th
Team 4 gets 4th, 18th, and 25th
Team 5 gets 5th, 15th, and 27th
Team 6 gets 6th, 19th, and 22nd
Team 7 gets 7th, 11th, and 28th
Team 8 gets 8th, 17th, and 21st
Team 9 gets 9th, 14th, and 23rd
Team 10 gets 10th, 12th, and 24th

So now everyone has three different teams to cheer for during the regular season, and whoever has the largest total amount of victories between their three teams after week 17 wins the pool.